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Investigation of DNA protective, antioxidant and antibacterial activities of water and methanol extracts of Oxalis triangularis

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Abstract (EN)

Plants are used in the treatment of many diseases in the world. Since our country has different climatic and ecological conditions and its flora includes many plant species and diversity, medicinal plants are used as an alternative treatment in our country. In this study, the total oxidant / antioxidant level (TOS / TAS) of leaf extracts of Oxalis triangularis plant, antibacterial effects, and DNA protective potential against Stenotrophomonas maltophilia bacteria were studied. The leaves of Oxalis triangularis were dried in the shade and extracts were obtained with the help of water and methanol solvents. Total oxidant / antioxidant levels were measured using TAS and TOS assay kit (Rel Assay Diagnostic) ready-made leaf extracts. Antibacterial activity was studied by the disk diffusion method. DNA protective activity was studied with pBR322 plasmid DNA using H2O2 and UV. As a result of the study, it was observed that the TAS values in Oxalis triangularis leaves were the highest in methanol extracts, while the TOS values were found to be the highest in the water extract. It was observed that there was no antibacterial effect on the bacterium Stenotrophomonas maltophilia. In the DNA protective activity study, it was determined that water extract had a protective effect.

Author

Resmiye Yalçınkaya

How to Cite

Resmiye Yalçınkaya (Master Thesis). Investigation of DNA protective, antioxidant and antibacterial activities of water and methanol extracts of Oxalis triangularis, 2021, Gaziantep University.

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