Synthesis and investigation of structural properties of 8-t-butyl-4-methyl coumarin

This study presents the experimental synthesis of the compound 8-t-butyl-4-methylcoumarin, quantum chemical calculations, and examination of its biological properties such as antibacterial, antifungal, and antioxidant. 8-t-butyl-4-methylcoumarin compound was synthesized by the reaction of ortho t-butyl phenol and Ethyl acetoacetate compound. The synthesized 8-t-butyl-4methylcoumarin compound was experimentally illuminated by spectroscopic techniques such as FT-IR, 1H-NMR and 13C-NMR. In addition, the experimentally obtained 8-t-butyl-4-methylcoumarin compound was theoretically studied using methods such as Gaussian and Density Functional Theory (DFT) methods. It has been observed that the findings obtained as a result of both experimental and theoretical studies support each other. Finally, biological activities such as antibacterial, antifungal and antioxidant of the 8-t-butyl-4-methyl coumarin compound were examined.