Investigation of the determinant effect of the PIRO and CURB-65 scale on morbidity and mortality in COVID 19 patients installed from the emergency department to intensive care unit
2023
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Advisor: Doç. Dr. Mehmet Esen
Abstract (EN)
Introduction and Aim: It emerged in Wuhan, China in December 2019 and was declared a global pandemic by the World Health Organization on March 11, 2020. In order to make a decision about the intensive care, service or home follow-up of Covid-19 patients, the mortality levels and needs should be evaluated quickly. The use of scoring systems can help emergency and intensive care physicians evaluate patients more effectively and quickly. This study was conducted to investigate the usability of the CURB-65 and PIRO scales in determining the intensive care needs and mortality levels in Covid-19 patients. Materials and Methods: The population and sample of our study consists of patients who applied to the emergency department of Amasya Sabuncuoğlu Şerefeddin Training and Research Hospital and were admitted to the intensive care unit. CURB-65 and PIRO scores were determined with the data obtained from the hospital information system, and blood parameters were recorded at the same time. The obtained data were recorded with the SPSS Statistics 22 data program. The normality of continuous variables was evaluated with the Shapiro-Wilk's test, and the homogeneity of the variances was examined with the Levene test. The Significance of Difference Between Two Means test was used for the difference between the two groups. Chi-square test was used for the relationship between qualitative variables. Quantitative variables were presented as arithmetic mean ± standard deviation and qualitative variables as numbers and percentages. Pearson correlation coefficient was used for the relationship between quantitative variables. Results: 100 patients were included in the study. 58% of the patients were male and 42% were female. 39% of those who were considered as missing were male and 28% were female. 67% of the patients died in the intensive care unit, and 33% were taken to the intensive care unit. The mean age of the patients was 68.93. The mean CURB-65 score was 2.52, the PIRO score was 2.79, the Glasgow score was 12, and the mean day of hospitalization was 14.78. 40% of the patients did not have any additional disease. ), 9% patients had ARF+CRF, 5% had CHF, 15% had HT, 4% had Asthma-COPD, and 16% had DM+HT. Statistically significant age was found between the patients who died in Covid-19 patients and those who were transferred to the ward (p<0.001). A significant correlation was found between the CURB-65 and PIRO Scales (p<0.001). The CURB-65 and PIRO scores were found to be significantly higher in the deceased patients than the patients admitted to the service (p<0.001). The Glasgow Coma Score was found to be significantly lower in the deceased patients than the patients admitted to the service (p<0.05). The PLT value was found to be significantly lower in the deceased patients than the patients admitted to the service (p=0.001). Conclusion: CURB-65 and PIRO scores were found to be significantly higher in deceased patients than in patients admitted to the service. A significant relationship was found between CURB-65 and PIRO in all groups. We think that the CURB-65 and PIRO scales are effective in the decision of intensive care-service hospitalization and discharge of Covid-19 patients and as a mortality indicator. Keywords: Emergency Service, Covid-19, CURB-65, PIRO
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Dr. Tuba Güler
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Tuba Güler (Master Thesis). Investigation of the determinant effect of the PIRO and CURB-65 scale on morbidity and mortality in COVID 19 patients installed from the emergency department to intensive care unit, 2023, Tokat Gaziosmanpaşa Üniversity.
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