Afyonkarahisar health sciences Universitythe effect of neutrophil/lymphocyte ratio, anemiaand thrombocytopenia on mortality in patientsinstalled in the intensive care unit of the hospital

Objective: Mortality rates are high in patients hospitalized in intensive care units. Research continues to reduce mortality rates. In our study, hemogram in intensive care patients parameters of neutrophil /lymphocyte ratio, anemia and thrombocytopenia. It was aimed to evaluate the effects on mortality . Material–Methods: This retrospective study was conducted with 220 patients, 117 men (53.2%) and 103 women (46.8%), who were followed up in Afyonkarahisar Health Sciences University Hospital Internal Intensive Care Unit between January 2019 and December 2020. has been carried out. Our work; While all patients aged 18 and over, 90 years and under were included; Patients with a diagnosis of malignancy and patients staying in the intensive care unit for less than 48 hours were not included. In the complete blood count of the patients during their admission to the intensive care unit; neutrophil, lymphocyte, neutrophil /lymphocyte ratio, hemoglobin and platelet values, in biochemistry studies; Creactive protein, creatinine, bilirubin, ALT, procalcitonin values, fibrinogen and INR values in coagulation tests were noted. APACHE II and SOFA scores at admission were calculated. The relationship of these values with mortality was examined. In addition, neutrophil/lymphocyte ratio, anemia and thrombocytopenia The effect on survival was examined. Results: In our study, 220 patients, 117 men (53.2%) and 103 women (46.8%), were evaluated. The median age of the patients was 72 years (IQR=18.75). Concomitant disease was present in 88.18% (n:194) of the patients. The most common comorbidities are hypertension (42.7%; n:94), diabetes mellitus (30.4%; n:67), coronary artery disease (30.4%; n:67), cerebrovascular diseases (23%; n:51), chronic kidney disease (16.3%; n:36) was detected. The most common reason for admission to the intensive care unit was sepsis (29.5%). Sepsis mortality It was found that it affected (p=0.003). The reasons for hospitalization in the other intensive care unit are respectively; acute cerebrovascular diseases (22.2%), acute lung diseases (16.3%) and acute kidney diseases (13.1%). Anemia was detected in 59.1% of the patients included in the study. When the effect of anemia on survival by gender was examined, no significant difference was found. Thrombocytopenia was found in 27.27% of the patients included in the study. While 73.3% of these patients exited , 26.7% were discharged (p=0.02). Thrombocytopenia it was found to have a significant effect on survival (p=0.01). The effect of neutrophil /lymphocyte ratio on survival was not statistically significant ( p=0.571 ). Conclusion: As a result of our study, it was seen that hemoglobin and thrombocyte levels were effective on mortality in intensive care patients. While neutrophil/lymphocyte ratio and anemia had no effect on survival, thrombocytopenia It was found that there was a statistically significant effect on mortality and survival. Therefore, we think that complete blood count parameters, which are easily accessible in intensive care units, can be used as important markers in the prediction of mortality.