Arginase activity and oxidative markes imbalance in patients with chronic diabetes mellitus complication

In the world, diabetes kills both adults and children. During a two-month period, 100 diabetics and 35 healthy controls collected 135 blood samples. Patients with anemia, hepatitis, or hypertension were excluded, as sampled from women over sixty and pregnant women. After separation, the serum was kept at -20 oC. Total protein, albumin, globulin, amino, carbonyl, and thiol groups were isolated. All samples had arginase enzyme activity. Second, the current study included a statistical investigation of the parameter-arginzyme correlation. The research's findings Diabetics have higher levels of arginase in their blood serum than healthy controls (P0.05). Diabetes patients reported reduced levels of total protein, albumin, and globulin, all at (P0.05). An increase in free amino acid content in patients relative to healthy controls (P0.05). The carbonyl group concentration decreased inpatients and increased in diabetics at the probability threshold of (P0.05). NO, and MDA concentrations increased in patients compared to healthy controls.