Assessment of the level of oxidative stress and some biochemical variables among people with T2DM in Kirkuk governorate

The current study aimed to estimate the levels of llipid profile and oxidative stress in T2DMM patients compared to healthy controls. 120 subjects (males and females) patients suffering from T2DMM and 30 non-diabetics subjects (control) were used in this study. All subjects are adults aged between 30-70 years. The study was done in different hospitals in Kirkuk city, in the period from October 2021 to January 2022. A glucose level in serum of T2DMM patients shows a significant (P <0.05) increase than healthy subjects. A uric acid level in serum of diabetes mellitus patients shows a significant (P <0.05) increase compared to control group. Lipid profile showed significant (P<0.05) increased and decreased in between studied groups. Malondialdehyde levels showed a significant (P <0.05) increase in patients of diabetes type II compared with control group and significant (P <0.05) decreased in antioxidant enzymes. It's concluded that the both types of diabetes mellitus type II lead to induces oxidative stress and significant (P <0.05) differences in Lipid profile.