Darbe çekici cihazi kullanarak insan karaciğerinin ve patolojik durumlarinin frekansa bağli malzeme özelliklerinin karakterizasyonu

The current methods for characterization of frequency-dependent material properties of a whole human liver are very limited. In fact, there is almost no data available in the literature for the dynamic elastic modulus of healthy or diseased of human liver. We show that frequency-dependent dynamic material properties of human liver can be easily and more efficiently characterized by an impact hammer. The procedure only involves a light impact force applied to the organ by a hand-held hammer. The results of our experiments performed on 15 human livers freshly harvested from liver patients show that the proposed approach can successfully differentiate their level of fibrosis. We found that the elastic moduli of healthy and fibrotic livers vary from 10 to 20 kPa and 20 to 50 kPa for the frequency range of 0 to 100 Hz, respectively.