Comparison of the topical sericine(pure molecule derived from silkworm cocoons) treatment and the effects of emergency treatment methods on the wound healing in experimental contact burns

1% Silver sulfadiazine (SSD) is the mostly used agent among the drugs used for treating burnt wounds topically and there are many publications which study the use of SSD for different burn models. In the recent years, sericin which is one of the major 2 proteins of silk protein which is a natural polimer synthesized by epithelial cells found in silkworm has been shown to have proliferative effects on some cell membrane and to exert various biological activities. The literature review shows that the clinical and experimental studies on the effects of silk protein sericin on burn patients or experimental burn wound models is considerably few and inadequate. Therefore, it is aimed to determine whether sericin has an effect on healing of the healing of experimental contact type burn models and to compare its effects on burns with SSD which is accepted as a commonly used topical agent around the world.