Development of hydrogel containing tannic acid

This research investigates the water absorption capacity and release characteristics of hydrogel samples incorporated with tannic acid (TA) at different concentrations. The swelling test outcomes indicate that higher TA concentrations result in reduced water absorption capacity, while the release test demonstrates a release pattern influenced by pH levels. The greatest decrease in water absorption capacity is observed in hydrogel samples with the highest tannic acid concentration. Regarding release behavior, the hydrogel samples exhibit distinct patterns in buffer solutions with varying pH levels. The hydrogel sample containing 2.5% TA (w/v) shows the highest antioxidant activity. Considering the obtained data on release behavior and antioxidant activity, the hydrogel sample with 2.5% TA shows the best results. These findings underscore the significance of TA concentration and pH when formulating hydrogel samples for drug delivery and wound healing applications.