Retrospective evaluation of the mass lesions that diagnosed type 3 enhancing curve with dynamic contrast enhancing MRG

Aim: Breast cancer is one of the most common cancer among women.Mammography is basic method to screening breast cancer, but its spesificity is low.Breast MRG can show high sensitivity and specificity with its morphologic andenhancing features to determine the mass. Our aim is in this study to evaluate themorphologic features of mass lesions that determined type 3 enhancing curve with thedynamic contrast-enhanced MRG and benign-malign differentiation.Material and Method: Between January 2005-November 2009, the patients whowere done dynamic contrast-enhanced MRG and that the enhancing feature was type 3and the patients who were done a biopsy were evaluated as retreospective. Breast MRGobservations were actualized by using standard bileteral breast koil with the GeneralElectric(signa HDxt) 1.5 T MR device. The patients were classified according to theirfeatures of diagnosis, on which breast the mass was seen, dial, the mass dimension,shape, limit and signal. The patients who were getting neoadjuvan chemotherapyweren?t included to the study. In the dynamic serials, for time-signal bent,measurements that were taken from non-necrotic side of the mass at least 3 differentpoints were used.Results: One-hundred and seven patients were enrolled in the study. Mean agewas 44,63 years (±10,1 SD). Twenty-five patients (23,4%) was benign and 82 patients(76.6%) was malign diagnosis. Mean age and mass localization was no statisticallysignificant. When evaluated in terms of dimension, the average diameter of benignmasses was 12,7 mm (±10.5), and the diameter of malign masses was 23,93 mm(±15.47) (p<0.001). In terms of the morphologic shape, both of the groups weredifferent, benign masses were usually elliptic and regular bordered and malign masseswere formless and spiküle bordered (p<0001). Again when the signal features areevaluated 18 of the benign masses(72 %), and only 15 of the malign masses (18,3 %)had homogeneous signal. Again both of the groups were statistically significant.(p<0.001).Conclusion: With the dynamic breast MRG type 3 enhancing curve is notsufficient to make the discrimination of benign-malign. Morphologic features absolutelymust be used with the enhancing curve in the disciriminating diagnosis.Key Words: Dynamic breast MRG, Breast cancer, type 3 enhancing.