Pain and disability effect on quality of life at patients with diabetic polyneuropathy

Purpose: We aimed to investigatethe relationship and their effects onquality of life betweenviolence, disability, Sociodemographic characteristics, sex, metabolic parameters, typeofneuropathic pain at diabeticpolyneuropathy (DPN) diagnosi clinical and/or electrophysiological verified patients. Materials and Methods: Clinicaland/ornerve conduction studiesin patients with distal symmetrical peripheral neuropathyall with a confirmed diagnosis; biochemical assessment, Assessment quality evaluate Scale (PQAS) in order to evaluatetype andseverity ofpain, Brief Disability Questionnaire (BDQ) in disability evaluation, Short Formthequality of life assessment36 (SF-36) questionnairewas used. Results: (59.68%) 37 of62 patients were female, (40.32%) 27 of 62 patients of the study were male. Women's of average age is 59,89. Men's of average age is 63,8. There wasn't determined thesignificant relationshipbetweenpatientgender, socio-demographic characteristicsand quality of life (p> 0.05). The most common type of Neuropathic pain was burning(kindling). The significant relationship wasn't determined between pain severity between the sexes, disability and quality of life (p> 0.05). Disease duration were classified as <5 years, 5-10 years,> 10 years. The patients of disease duration > 10 years were significantly worse in the evaluations of the average quality of life with PQAS, BDQ and SF -36 questionnaire than the other two groups (p <0.001). Significant relationship between with HbA1c, pain intensity and quality of life was determined(p <0.001). But the significant relationship wasn't determined between HbA1c and disability(loss of ability)(p> 0.05). The evaluations between With the lipid profile; PQAS, BDQ and SF -36 questionnaire wasn't determined significant relationship (p> 0.05).The quality of life of patients are detected DPN as Electrophysiological was significantly worse than those who are not detected DPN. When Neuropathicpain symptoms were examined as temporary, changing and not changing of time's course, The average quality of life unchanging course of disease was determined significantly lower than the average of temporary group as time's coursetime course(p =0.01). When the deepand superficialpain values at locatedin the PQAS sub-groups increases, significantly reducedquality of lifewere observedandthe degree ofthis increasewasalsomoderate (r=-0,373; p=0,003; r=-0,463; p<0,001). When the eachtype of neuropathic pain compare to thequality of lifewas determined significantlycorrelate between quality of life and Pain, stinging, burning, discomfort, tenderness, numbness, tingling, cramping,the VisualAnalogue Scale(VAS) of thepainfulsymptoms (p <0.001). Conclusion: The DPN is one of the most important long-term complications of diabetes. Although still complication rates and in decreasing the mortality still continue be important factors too. Prevention strategies and patient education in the formation of DPN, determination of neuropathic pain types, measurements of the quality of life are important for these patients is important for the future treatment plan. The use of multiple scales that including general and disease-specific measures and using these measurements as a guide and evaluate the treatment interventions is important at type of neuropathic pain and determining quality of life. Key Words: Diabetic Polyneuropathy, Nerve Conduction Studies, Pain Quality Assessment Scale, Disability, Quality of Life