Factors affecting the long lasting of COVID-19 patients followed in the infectious diseases service at Duzce University Research Hospital

The new coronavirus disease (COVID-19), which emerged towards the end of 2019 and caused a pandemic all over the world, infected millions of people all over the world in 2020. Nowadays, studies on COVID-19 are increasing and information changes day by day. Our aim in this study is to determine the factors affecting the length of stay of patients hospitalized with the diagnosis of COVID-19. 102 patients hospitalized in our hospital's infection ward between March 2020 and June 2020 were included in the study. Age, gender, comorbid diseases, vital signs, leukocyte, neutrophil, lymphocyte, monocyte, hemoglobin, platelet, mean platelet volume (MPV), aspartate aminotransferase (AST), alanine aminotransferase (ALT) urea, creatine, c-reactive protein (CRP), procalcitonin, d-dimer, fibrinogen, lactate dehydrogenase (LDH), creatinine, prothrombin time (PT), international normalized ratio (INR), procalcitonin (pct), d-dimer, ferritin, troponin, neutrophil / lymphocyte ratio (NLR) platelet-lymphocyte ratio (PLR), monocyte-lymphocyte ratio (MLR) and MPV-lymphocyte ratio values were analyzed retrospectively. Parenchymal involvement in COVID-19 PCR, hospitalization tomography were classified. The antiviral, antibiotic and other supportive treatments they received and the length of their hospital stay were included. For statistical analysis, the distribution of the data was examined using the Kolmogorov-Simirnov test. Statistical analyzes were made with SPSS v.22 package program, the level of significance was taken into account as 0.05. 51 male and 51 female patients were evaluated in our study. The mean age of the patients was 56.51 ± 15.48 years. Average hospital stay was 7.58 ± 3.35 days. The patients were evaluated as longer and shorter hospitalizations than five days, and longer and shorter hospitalizations than seven days. Longer hospital stays were observed in patients with DM, HT, malignancy and those receiving favipravir, enoxaparin and vitamin C supplements. Fever, procalcitonin, AST and LDH values iv were found to be significantly higher in patients who were hospitalized for a long time compared to patients with a short hospitalization period. Lymphocyte count and percentage, neutrophil-lymphocyte ratio, monocyte count, mean platelet volume (MPV) lymphocyte ratio values were found to be significantly lower in long hospitalized patients. Key Words: COVID-19, comorbidity, hospitalization, lymphopenia, LDH, procalcitonin, CRP, Ferritin, D-dime