Investigtion of effect of ellagic acid on some hematological and antioxidant parameters in scaly carp (Cyprinus carpio)

In the present study was aimed to investigate the effects of various levels of dietary ellagic acid on growth performance, haematological values and antioxidant status in scaly carp (Cyprinus carpio). Fish were fed with the control diet and three different experimental diets containing three graded levels of ellagic acid (50, 100 and 200 mg kg-1 diet) for 60 days. On 30th and 60th days of experiment, the growth performance [live weight gain, relative growth and specific growth rate], haematological values [red and white blood cell counts, haemoglobin and haematocrit levels and erythrocyte indices: mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC)] and oxidant/antioxidant parameters [malondialdehyde level, catalase and glutathione-S-transferase activities and reduced glutathione level] were analysed. There was no statistically significant difference in the live weight gain, relative growth and specific growth rates of the control and ellagic acid treated groups. The red and white blood cell counts, haemoglobin and haematocrit levels increased in the groups fed with EA when compared with the control group. However, there were no significant differences in the erythrocyte indices among the groups. When compared to the control group, the liver and kidney malondialdehyde levels of ellagic acid treated groups were significantly decreased. The liver and kidney catalase and glutathione-S-transferase activities and reduced glutathione levels of ellagic acid treated groups were significantly increased when compared to the control group.