Investigation the relationship of athletic performance between cognitive process with genetic diversity in young basketball players

The relationship between the athletic performances (strength, speed, endurance and flexibility) cognitive emotional states (hopelessness, anxiety, depression) of young basketball players and the 9 genotypes, which are their genetic markers, were compared with a multiple perspective at the SNP level. A total of 17 athletes from the Galatasaray U15 men's team (14-16 age range), playing in the basketball youth league participated in the research. Performances of young basketball players; CK-MM (rs1803285), IGF-2 (rs3213221), MCT-1 (rs1049434), IL-6 (rs1800795) genotypes, (cognitive status); BDNF (rs6265), 5HTT (rs25531), MAOA (VNTR) and (injury status); GDF-5 (rs143383), IL6R (rs2228145) were compared with genotypes. Binary grouping of genotypes was made in (Independent Samples T-Test), three or more comparisons (One Way ANOVA), and Post-Hoc, Bonferroni and Games-Howell for significance comparisons. Were found that with low body fat percentage associated IL-6 GG genotype (p=0.042), with low BMI associated CK-MM GG (p=0.013), IGF-2 GG (p=0.001), IL-6 GG (p=0.018), in young basketball players. In addition, athletes; CK-MM AG (p=0.045), IL-6, GG (p=0.001) high vertical jump, CK-MM AA (p=0.038) IL-6 CC (p=0.009) with low vertical jump performance, IL -6 CC (p=0.041), MCT-1 AT (p=0.048) lower MaxVO2 performance, IGF-2 GC (p=0.002), MCT-1 AT (p=0.046) genotypes with statistically low blood lactic acid accumulation were found to be related. In the cognitive status comparison of the athletes; BDNF AA homozygous, MAOA Warrior genotypes with high hopelessness and anxiety mood (respectively) [(BDNF AA p=0.045, p=<0.001), (MAOA Warrior p=0.001, p=0.014)], BDNF GG homozygous and G allele and MAOA Normal genotypes low hopelessness and anxiety mood, with (respectively) [(BDNF GG p=0.010, p=0.007), (MAOA Normal (p=0.008, p=0.015)] 5HTT AA homozygous (p=0.037) high GG homozygous (p=0.027) was found to be statistically associated with low depression mood. Injury states and the GDF-5 T allele (in terms of crippling potential) have been confirmed to be the risky allele. This research concerned with molecular predictors of young basketball players has been highlighted a number of potentially important DNA polymorphisms contributing to predisposition to success in certain types of sport.