Corelation Between Blood Limits of MDA, SOD, Katalaz And Peritonit strength on the Patiens With Generalized Peritonitis.

Generalized peritonitis term is used as synonym with intraabdominal infection and it constitutes an important part of emergent surgical interventions. The aim of this study is to determine the strength and proceded efficiency of MDA, SOD, and catalase levels that are indicators of oxidative stress in generalized peritonitisThis study was conducted as prospective and randomized with patients who applied at Dicle University, Faculty of medicine, Clinic of General Surgery between March-September 2008. Patients were composed as group 1 (n=50), who had generalized peritonitis laparotomy; group 2 (n=50) who had laparotomy under elective conditions and who did not have table of peritonitis; and group 3 (n=50) as control group. In order to measure limits of MDA, SOD, CRP and catalese, blood samples were drawn from the patients in group 1 and group 2 on 0. 1st and 3rd days.However, venous blood samples were drawn from Group 3When making statistical evaluation, one-way Anova test was used to compare the average of intergroup parametric variables. Repeated Anova test was used to compare intragroup parametersWhen the MDA values of group 1 on 0. 1st 3rd, day were compared to group 2 and group 3, the difference was found statistically meaningful. It was found out that there was a difference between the MDA averages of group 1 and group 2 on 0. 1st 3rd, dayWhen the catalase values of group 1 and group 2 on 0. day were compared to catalase value of group 3, meaningful statistical difference was found. When the catalese values of group 1 and group 2 on 3rd day were compared to group 3?s catalase value, statistically meaningful difference was foundAmong the catalase values of group 1 and group 2 on 0. 1st, and 3rd day statistically meaningful difference was foundWhen the SOD values of group 1 and group 2 on 0. day were compared to SOD value of group 3, meaningful statistical difference was found. Between the SOD values of group 2 on 1st day, and SOD values of group 3, statistically meaningful difference was found. Between the SOD values of group 1 and group 2 on 3rd day and SOD values of group 3, statistically meaningful difference was observedWhen the SOD values of group 1 and group 2 on 0. 1st, and 3rd. day were correlated with SOD value of group 3, statistically meaningful difference was foundWhen the CRP values of group 1 and group 2 on 0. 1st, and 3rd. day were compared , meaningful statistical difference was detected. When there was a difference between values of group 1 on 0. 1st, and 3rd days, the difference between the values of group 2 on 0. and 3rd days and 1st and 3rd was found meaningfulConsequently, we consider limits of SOD, MDA and catalases as usable parameters for the following and detection of generalized peritonitis strength.