Ibn Alnafees hastanesi acil durum bölümüne katılan hastalarda kalp yetmezliği olan hastalarda B tipi doğal peptit düzeyleri

This study was conducted on 130 subjects to investigate some of the biochemical changes that happens during heart failure condition. Eighty subjects of the 130 were diagnosed with heart failure while the rest 50 were healthy to control the study. B-Type Natriuretic Peptide (BNP), troponin T, creatinine, fasting blood sugar (FBS), lactate dehydrogenase (LDH) activity, triglycerides, total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and very low-density lipoprotein (VLDL) were analyzed for each subject. The results have shown significant increase in the levels of BNP, troponin T, and creatinine in heart failure patients compared to control. Moreover, the activity of LDH was increased significantly in heart failure patients compared to control. FBS on the other hand did not change significantly between patients and control. The lipid profile parameters were changed significantly in heart failure compared to control. In conclusion, heart failure has shown strong effect on the renal function, and BNP has played significant role in the pathophysiology of heart failure.