The effect of baseline and control levels of CRP on the prognosis of patients admitted to the hospital from the emergency department

The Effect of Baseline and Control Levels of CRP on the Prognosis of Patients Admitted to the Hospital from the Emergency Department Objective: COPD is a major threat to public health or one of the leading causes of chronic morbidity and mortality in the world. The objective of this study is to determine whether the desired C-Reactive Protein (CRP) and leukocyte counts during hospitalization and admission in patients with COPD admitted to the hospital by referral to the Emergency Department are on mortality and prognosis Method: Patients with COPD exacerbation who presented to the Akdeniz University Hospital Emergency Department and admitted to either Pulmonary Diseases Ward or Intensive Care Unit during 01/01/2016-12/31/2016 were included in the study. For each patient CPR value, leucocyte number, blood gas values, disposition and received treatment with the demographic characteristics and comorbid diseases were analyzed and effect on 90-day mortality were investigated. Results: P value for Emergency Department CRP is 0,257; p values during follow up were 0,938, 0,581 and 0,180 and none of the CRP values showed any short term mortality benefit. For the mean value of leukocyte counts was calculated in Emergency Department as p = 0,051 and 0,046, 0,000 and 0,000 in p values for leukocyte counts after hospitalization With a cut-off value of 10,8×10³/mm³ for leukocyte count, high leukocyte values in Emergency Department were statistically significant for mortality [OR = 1,92(1,05-3,52%95 CI)]. PaCO2 and HCO3 values were found to be significant in predicting mortality (respectively 0,015 and 0.011). Discussion: The CRP values tested in Emergency Department and after admission are not predictive of the mortality of patients with COPD exacerbations. Leucocyte values at the time of admission and after admission, 38 PaCO2 and HCO3 levels in the emergency department were found to be statistically significant for a 90-day mortality estimate. Key words: COPD exacerbation, CRP, mortality