Diabetes frequency in patients with colon cancer, relationship between diabetes and prognostic factors

Objective: Diabetes; is a chronic inflammatory disease. Previous studies have shown that diabetes worsens colon cancer prognosis and increases cancer-related mortality. The aim of our study was to evaluate the incidence of diabetes in colon cancer patients and the relationship between diabetes and prognostic factors. In our study we tried to answer the following guestions: What is the effect of diabetes on prognosis in patients with colon cancer? Are colon cancer patients with diabetes diagnosed at a later stage than colon cancer patients without diabetes? Method: The study was conducted between September 2018 and April 2019 with 547 colon cancer patients, patients with newly diagnosed disease, patients on cheomoterapy and patients in the surveillance period were included. Data; Patient information form, disease-related characteristics form, patient files and obtained from hospital automation system And informed consent was obtained from all patients. The assessment was conducted during the first face-to-face interview with the patient. Results: 40.8% of the patients were female and 59.2% were male. The mean age of the patients was 62.48 ± 11.88 and 62.56 ± 13.70 in stage 0-1, 63.54 ± 10.98 in stage 2, 61.76 ± 12.77 in stage 3, and 61.88 ± 11.00 in stage 4. It was found that 21.9% of patients with colon cancer were also diagnosed with diabetes mellitus. It was found that 66.38% of the patients with diabetes had a diagnosis period of 5 years or more. It was found that 14.4% of the patients used oral antidiabetic drugs, 4.2% used insulin and 2.4% used oral antidiabetic drugs and insulin as antidiabetic treatment. As a result of statistical analysis, there was no significant difference on the stage of colon cancer compared to patients without diabetes mellitus (p = 0.862). The oral antidiabetic, insulin or oral antidiabetic and insulin use of the patients did not differ significantly in the stage of colon cancer (p = 0.915). Conclusion: Colon cancer patients; the diagnosis of diabetes was not associated with the stage of the disease. Key words: Colon Cancer, Diabetes Mellitus, Prognostic Factors