Comparing of gastrointestinal system symptoms and disorders of patients with chronic renal failure who having conservative treatment and different renal replacement treatments

Chronic renal failure (CRF) affects gastrointestinal system as affected all theother systems and causes histological, functional and mucosal changes ingastrointestinal system. Gastrointestinal complaints and complications are very commonin CRF and these may worsen the life-quality of patient, may increase morbidity andmortality of CRF, consequently. Furthermore, it is emphasized that this complaints andsymptoms differ among the treatment modalities of CRF. For this reason; determiningof gastrointestinal system complaints and symptoms, their relationship with treatmentmodality, finding out underlying reasons and treatments of these gastrointestinaldiseases are important for increasing life-quality of patients with CRF and decreasingmorbidity and mortality of CRF.We aimed to determine the frequency of gastrointestinal system complaints andsigns in patients with CRF and to determine if these complaints and signs changebetween treatment modalities. 97 patients followed in predialysis period, 92 patientsunder treatment of peritoneal dialysis, 101 patients under treatment of hemodialysisincluded to this study. Gastrointestinal complaints and diseases, backroundcharacteristics of patients and drugs they used were questioned to the patients with faceto face conversation, forms were filled and examinations of all patients were made.Results of upper gastrointestinal system endoscopies, colonoscopies, abdominalultrasonographies and abdominal tomografies of patients, performed in last threeemonths were evalueted.Results were compered between predialysis, hemodialysis and peritonealdialysis patient groups. The most common complaints were dispepsia (%50), nause(%45), epigastric pain (%44), anorexia (%38), belch (%36), vomiting (%32),constipation (%32) and gastroesofagial reflux among all patients, generally.Gastrointestinal disorders like gastritis (%62), gastroesophagial reflux (%39),hemorrhoids (%19), irritable bowel syndrome (%14), GIS bleeding (%14),cholelithiasis (%11) were frequent in patients. Ratio of patients with weight lose was%20 in predialysis and %8 in PD and the ratio was higher in predialysis groupsignificantly (p=0,016). Belch was present %46 in PD group and %31 in HD group andratio was higher in PD group than HD group significantly (p=0,032). It is found thatgastritis ratio %70 in PD , %55 in HD, hemorrhoids ratio %24 in PD, %12 in HD,esophagitis %8 in HD, %0 predialiysis, hiatal hernia %0 in predialysis group, %5 in HDgroup and %0 in PD group. Gastritis and hemorrhoids ratio was higher in PD than HDsignificantly (p=0.043, 0.028), otherwise there wasn?t difference between PD andpredialysis group, significantly. Esophagitis ratio was higher in HD than predialysissignificantly (p=0.004) and hiatal hernia ratio was higher in HD group than both PD andpredialysis groups significantly (p=0,025, 0,026). There wasn?t statistical differanceabout the other complaints and signs between the groups.Results of this study showed that; gastrointestinal symptoms and disorders werevery common in CRF, beside of this; while gastritis and hemorrhoids were morefrequent diseases in peritoneal dialysis group, esophagitis and hiatal hernia were morefrequent in hemodialysis group. Except this; frequency and distribution of the othersymptoms and signs didn?t differ among treatment modalities, generally. This study isvaluable because of eveluating the gastrointestinal complaints and symptoms bycomparing between treatment modalities of CRF. More studies are necessary thateveluetes prevelance of gastrointestinal symptoms among treatment modalities, affectsof treatment modalities on gastrointestinal system and underling mechanisms ofgastrointestinal changes and disorders in CRF.