Evaluation of bone - mineral disorders, anemia, cardiovascular disorders in chronic hemodialisis patients

The prevalence of cardiovascular disease, bone-mineral disorders and anemia in patients undergoing chronic hemodialysis is higher than the normal population. It is known that the prevalence of cardiovascular disease in chronic kidney disease and dialysis patients is 4-6 times higher than in the normal population. Additionally, as parenchymal loss continues in these patients, deteriorations in bone-mineral metabolism continue to occur. Anemia in chronic kidney disease is considered one of the most important and frequent complications that negatively affects the quality of life. In this study, we aimed to investigate cardiovascular disease, anemia and bone mineral disorders in patients undergoing chronic hemodialysis. Materials and Methods: In our study, the data of patients who received hemodialysis treatment in the Nephrology Clinic Dialysis Unit of Van YYÜ Faculty of Medicine Hospital be-tween 01.07.2021 and 01.07.2022 were retrospectively examined. The study was conducted on a total of 56 patients receiving hemodialysis treatment (n: 56). Demographic characteristics of the patients, ECHO and DEXA results; hemogram, biochemistry, hormonal and vitamin tests; It was obtained retrospectively from drug use files. Since the study was planned retrospectively, sample size was not calculated. All the information obtained was transferred to the computer environment. Descriptive statistics were used to analyze the data. Looking at descriptive statistics; Expressed as mean, standard deviation, minimum, maximum, number (n) and percentage (%). SPSS (IBM SPSS for Windows, ver.25) statistical package program was used in all analyses, and p<0.05 was considered significant for the significance level. Results: The average hemoglobin of 56 patients included in our retrospective study was de-termined as 11.42 ± 1.83 g/dl in men and 10.27 ± 1.95 g/dl in women. A statistically significant difference was found between the hemoglobin values of the patients according to their gender (Z=-2.361; p<0.05). The average hematocrit of the patients was determined as 35.65 ± 5.53% in men and 32.33 ± 5.96% in women. A statistically significant difference was found between the hematocrit values of the patients according to their gender (t=-2.149; p<0.05). Of the 56 patients included, cardiovascular disease was detected in 34 (60.7%), osteoporosis in 23 (41.1%), and anemia in 44 (78.6%). Conclusion: In our study, it was observed that the likelihood of CVD, osteoporosis and anemia complications increased in patients undergoing chronic hemodialysis.