The evaluation of upper extremity functions in patients with obesity hypoventilation syndrome

Objective: The aim of this study is to comprehensively evaluate upper extremity functions in patients with obesity hypoventilation syndrome (OHS). In this context, the relationship between upper extremity exercise capacity, grip strength, and activities of daily living (ADL) was examined. Method: Thirty-one patients aged between 18-65 years who were diagnosed with OHS were included in our study. Polysomnography data of the patients were recorded, and the use of non-invasive mechanical ventilation was queried. Body composition was evaluated using the 'Tanita Body Composition Analyzer', and anthropometric measurements such as waist and hip circumference. Upper extremity functional exercise capacity was evaluated with '6-Minute Pegboard and Ring Test (6-PBRT),' and grip strength was measured with the 'Jamar Hand Dynamometer.' For the assessment of ADL, both a performance-based 'Glittre ADL Test' and a patient-reported outcome measure, the 'Milliken ADL Scale,' were used. Results: The mean age of the patients included in the study was 50,61±7,73 years, and the mean BMI was 35,51±3,65 kg/m². The mean number of rings carried in the 6-PBRT was 296,97±56,91, and the mean completion time for the Glittre ADL Test was 3,30±0,67 minutes. A strong negative correlation was found between the 6-PBRT and Glittre ADL Test (r =-0,659, p<0,001), a moderate positive correlation was found with grip strength (dominant hand r=0,394, p=0,028), and a moderate positive correlation was observed with Milliken ADL Scale (r=0,445, p=0,012). Conclusion: In this study, it was shown that 6-PBRT scores decreased and Glittre ADL Test completion time increased in patients with OHS. Higher 6-PBRT scores were found to be associated with shorter Glittre ADL Test times, higher Milliken ADL Scale scores, and increased grip strength. These results suggest that OHS may negatively affect not only respiratory functions but also musculoskeletal system functions. Keywords: Obesity hypoventilation syndrome, upper extremity, activities of daily living, 6-PBRT