To evaluate the early detection means and management of cranial changes using imaging methods of posterior reversible encephalopathy syndrome (pres) developing related to obstetric causes

Objective: We aimed to evaluate the early detection means and management of cranial changes using imaging methods of posterior reversible encephalopathy syndrome (PRES) developing related to obstetric causes. Method and Material: In this study, the data of 48 patients diagnosed with posterior reversible encephalopathy syndrome and of 37 with normal cranial imaging were evaluated at Dicle University Medical Faculty Obstetrics and Gynecology Clinic between January 2010 and December 2017. The patients were classified as Group-1 (Posterior reversible encephalopathy syndrome) and Group-2 (normal cranial imaging). Such data as demographic data, physical examination findings, laboratory parameters any current or previous surgical interventions performed in our hospital or elsewhere, the length of hospital stay, length of stay in intensive care units and whether patients were transferred to another clinic were obtained from hospital archive files and electronic archive database. Results: A total of 274 patients with severe preeclampsia and eclampsia were admitted to our clinic during this period of 7 years. Additional imaging modalities were asked from 94 patients who described neurological symptoms. Two patients with intracranial hemorrhage + DIC were seen to have ended up with maternal mortality. In this study, 48 patients (56.47%) diagnosed with posterior reversible encephalopathy syndrome were classified into group 1 and 37 patients (43.53%) with normal cranial imaging into group 2. A total of 85 patients were included in the study. ALT, PT and INR values were significantly higher in Group 1 patients than Group 2 patients (p <0.05). Platelet and albumin levels were significantly lower in Group 1 patients (p<0.05). Group 1 patients were hospitalized for 8.44 days and group 2 patients for 6.54 days. It was detected that 32 patients (66.67%) in group 1 and 20 patients (54.05%) in group 2 needed intensive care. It was found that 56 (65.88%) of the patients had first intervention in our clinic and 29 (34.22%) of patients were performed in an external center. Conclusion: In our study, when the Group 1 and Group 2 patients were compared, we found that values that were significant in terms of laboratory parameters could have a positive effect on prognosis if detected and intervened early and could be a predictive of posterior reversible encephalopathy syndrome for Physicians and we are of the opinion that this may contribute to the reduction of maternal morbidity and mortality. Key Words: Hypertension, preeclampsia, posterior reversible encephalopathy syndrome