Investigation of prooxidant and antioxidant effects of extracts from Phellinus igniarius (L.) Quél and Phellinus torulosus (Pers.) Bourdot & Galzin, species on the membrane of epidermoid carcinoma cells
2021
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Advisor: Prof. Dr. Aysun Özkan
Abstract (EN)
In this study, methanol, and water extracts obtained from Phellinus igniarius (L.) Quél and Phellinus torulosus (Pers.) Bourdot & Galzin, species were evaluated comparatively for their antioxidant and prooxidant activities on the membrane of epidermoid carcinoma (A431) cells and healthy fibroblast (Bj) cells. The prooxidant (cytotoxic) effect of P. igniarius and P. torulosus extracts on A431 and Bj cell lines was defined by MTT (3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide) test. In order to demonstrate the antioxidant effect of our extracts, the cells were exposed to H2O2 (IC50 and IC70), a strong oxidizing, for 24 hours after the pretreatment with extracts at different concentrations, (
Author
Dr. Bürke Çırçırlı
How to Cite
Bürke Çırçırlı (Master Thesis). Investigation of prooxidant and antioxidant effects of extracts from Phellinus igniarius (L.) Quél and Phellinus torulosus (Pers.) Bourdot & Galzin, species on the membrane of epidermoid carcinoma cells, 2021, Akdeniz University.
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