Relationship between growth hormone and juvenile idiopathic arthritis in Iraqi patients

Children with JIA often have growth retardation and are undersized for their age. Growth hormone (GH) has been shown to be an effective and safe therapy option for these individuals. The goal of this study is to examine the link between kids' growth hormone and juvenile idiopathic arthritis. A study was designed included two groups of children less than 18 years, 65 children of them were patients with JIA and other 65 Childs were healthy control. In this work, nine parameters include age, GH, Hb, AST, ALT, Urea, Creatinine, ESR, WBC, and height were measured in both patient children with idiopathic juvenile arthritis and healthy control. Mean and standard deviation of age, GH, Hb, AST, ALT, Urea, WBC in patients were more than in control group, but creatinine, ESR, and Height in patients were less than in control group. Also, the results of this study showed a negative relationship between JIA represented by ESR level in patients and growth hormone represented by Height with predictive equation of linear relationship as (- 0.0486x + 15.349). The study concluded that there is a relationship between GH and JIA in children.