Plasma lactate levels at single and multiple births in chios lambs

Lactate is an important metabolic fuel for cellular energy. Lactate production is a protective response to provide continued cellular energy during tissue hyperfusion or hypoxia and in reducing acidosis. Hyperlactemia is closely related to the severity of the disease. In addition, the use of lactate as a biomarker in human medicine and recently in veterinary medicine has increased. The aim of this study was to investigate the plasma lactate level and its relationship with survival in single, twin, triplet and quintuplets Chios breeds of lambs. The births of pregnant Chios breeds of sheep in Aydın Metropolitan Municipality Chios Sheep Production Farm were followed and blood samples were taken from single, twin, triplet and quintuplets lambs without sucking colostrum within 15 minutes after birth. When 12 samples were reached in each group, sampling was terminated. Plasma lactate levels of blood samples were run immediately with EUROLYSER Solo device. For other routine biochemical analyzes, samples were frozen at -20oC and glucose, total protein, albümin, urea, creatinine, cholesterol, triglyceride, AST and ALT analyzes were studied with commercial test kits. The results were evaluated statistically. According to these results, differences in plasma lactate, total protein, albümin and triglyceride levels were determined significant differences between the groups, but no significant difference statistically was found between the groups in glucose, BUN, urea, creatinine, AST, ALT and cholesterol levels. In this study, when the available findings were evaluated, high lactate levels was detected in single, twin, triplet and quintuplets births in terms of lactate levels. Elevated lactate levels was found to be more prominent in multi-lambs (in triplet and quintuplets lambs). Lactate levels are an important predictor of mortality in an emergency veterinary clinic and there is a negative correlation between survival and lactate concentration. In this study, it was concluded that the increase in the number of offspring in multiple births and lamb deaths were found to be correlated and the monitoring of lactate measurement would be meaningful in determining lamb survival. Keywords: Lactate, multiple births, sheep.