The relationship between cerebral lateralization and coronary artery disease, coronary artery anomaly, coronary artery dominance

Besides the well-known classic risk factors and newly described minor risk factors of Coronary Artery Disease; novel risk factors so-called ?geometric risk factors? are recently being investigated. The association of cerebral lateralization with other diseases were defined formerly. The aim of this study is to investigate the relationship between cerebral lateralization and Coronary Artery Disease, coronary artery anomaly, coronary artery dominance.1069 consecutive patients who underwent coronary angiography in our Clinics between May 2009 and March 2010 were included in the study.The coronary angiograms were evaluated by two cardiologists. In context of remarkable disagreement, a third cardiologist made the last discision. The presence and the stage of coronary arterial stenosis, the anatomic variations and coronary artery anomalies, coronary artery dominance and the shape of RCA (S or C) were defined.Hand preferences of the patients in regard to cerebral lateralization were defined with ?10 Items Edinburgh Questionaire? and subjects were divided into three groups as follows: left-handed, right-handed and ambidextrous. Age, height, weight and the presence of CAD risk factors of the patients were recorded.The statistical analyses were performed by ANOVA variant test, ki-square test and student?s t test. SPSS version 16.0; Statistical Package for the Social Sciences were used.There was no statistical difference between the three groups in context of CAD, coronary artery anomalies and coronary artery dominance. The median age was significantly lower in the left-handeds compared to the right-handeds. The median age of the ambidextrous patients were significantly different when compared to right-handeds. There was no difference between 38 left-handeds and 38 right-handeds with respect to coronary artery anomalies and coronary artery dominance. There was statistically signifcant difference in right-handeds with respect to presence and percentage of RCA lesions and presence and percentage of LMCA lesions. The percentage of the presence of ectasic segment in left-handeds were 8% and it showed limited significance