Clean and efficient synthesis of N-aryl and N-alkyl succinimides in sub-critical water

In this study, we propose an alternative, fast and clean method using sub-critical water with short reaction times. Although reaction of aliphatic amines needs more investigation, it?s possible to say that the reaction is general and applicable to aliphatic amines and aromatic amines. The literature doesn?t mention any example of succinimide synthesis in sub-critical water. Once again, other examples of synthesis of succinimides in organic solvents, uses succinic anhydride as starting material and with two steps to obtain target succinimide from succinic anhydride.