Production, application and characterization of silver nanoparticle doped hydroxyapatite coatings (AgNP/HAP) for titanium dental implants

In order to increase the rate of osseointegration and reduce the risk of infection in dental implant applications, silver nanoparticle added (AgNP) hydroxyapatite (HAP) nanoparticles were synthesized; The antibacterial activity of the synthesized coating material on three different bacterial species (S. aureus, E. coli, S. mutans) was investigated by agar well diffusion and agar disc diffusion methods. With using the parameters changed during the preparation of the production protocol, DLS and UV-Vis characterizations, AgNP synthesis was carried out at 60 nm in size with a PDI value of 0,088. The synthesized AgNP+HAP particles were applied to grade 4 (purity) titanium dental implants with using the Spray Coating method. Microstructure investigations on the implant material were performed with using scanning electron microscopy (SEM). AgNP synthesis was carried out at optimum values with repeated silver nanoparticle production processes, and antibacterial activity was demonstrated as a result of the doping of the synthesized AgNP to HAP. The applicability of the synthesized coating material to titanium implants for use in dental implant applications using the spray coating method has been discussed.