Effect of some biochemical parameters and humeral immunity on tsh receptors in thyroid disorders patients

TSH-R Ab is the better hyperthyroidism marker especially with patient's immune thyroid Graves' hyperthyroidism (GH) and Hashimoto's hypothyroidism (HH) are the opposite ends of the clinical expression of autoimmune thyroid diseases (AITD). In this study 50 patients with thyroid dysfunction and a control group consisting of 50 healthy. Elevated TSHR-Ab levels, it was associated with an increase in FT4, FT3, and T.G with decreased TSH level, so it had an immune response. The values of interleukin -6 and TNF are also increased. The results show a significant increase between TSH-R Ab with FT4, FT3, and T.G in patients with control and also male with a female when compared with controls. The results show that was a clearly significant decrease between TSH-R Ab with TSH among patients, control, and even males with females. Decrease significantly with S.C, TG, and LDL-C among patients, control because hyperactivity for thyroid secretion and HDL no significant. The results show a significant decrease with S.C, HDL, and LDL-C in males and females,s and T.G no significant. Our study showed a positive correlation between TSH-R Ab with FT4, FT3, T.G, TNF, and IL-6 while being a negative correlation with TSH.