Comparison of the effects of different platelet concentrates on palatal wound healing

Aim: The aim of this study was to compare the effects of AFG and i-PRF on palatal wound healing and postoperative discomfort. Material and Method: In this study, 36 patients in need of FGG were divided into three groups. AFG (n=12) or i-PRF (n=12) was applied to donor sites and compared to control group (n=12). Wound healing with H2O2 test, VAS, MMS scale and LTH index were evaluated on the 3rd, 7th, 14th day and 1st month. The bleeding status was evaluated on 3rd and 7th days. Palatal tissue thickness was measured at baseline, 1st month and 3rd month. Results: Epithelialization was higher in the test groups on the 14th day than the control group(p<0.05). MMS scores at 3rd and 7th days were higher in the control group than in the test groups(p<0.05). MMS scores at 14 days and 1 month were lower in the AFG group compared to the control and the i-PRF group(p<0.05). In the AFG group, LTH levels at 3rd, 7th, 14th days and 1 months were higher than control and i-PRF groups(p<0.05). VAS scores of the AFG group were lower than the control and i-PRF groups at the 7th postoperative day(p<0.05). Bleeding was lower in the test groups than in the control group(p<0.05). There was no statistically significant difference between the groups in terms of tissue thickness(p>0.05). Conclusion: AFG and i-PRF have positive effects on the healing process by accelerating wound healing and reducing postoperative morbidity. Within the limitations of this study, AFG has superior properties in wound healing compared to i-PRF.