The antimutagenic activity of the garlic which preapared by different methods

In this study, the anti-mutagenic activity of the garlic extracts whichprepared by different methods was investigated against the mutagenic effects ofHydrogen peroxide (H2O2). For this purpose, six different garlic extract were used.Hydrogen peroxide (H2O2) was used as positive control and one night aged tapwater was used as negative control in this study. For this purpose, broad bean (Viciafaba L) seeds which were used as experiment material were treated with differentaqueous garlic extracts in different concentrations (0.025ml/ml and 0.25ml/ml) afterthan mutagen treatment. Garlic extract treatments increased the dividing cell rate(mitotic index), which has been decreased after than Hydrogen peroxide (H2O2)treatment. Chromosomal aberration frequency was changed depending on garlictreatments. Fresh garlic extract and garlic powder extract treatments were moreeffective than the other garlic extracts. It was found that heated garlic extractsshowed slight effects on mitotic index and chromosomal aberrations. When the twotreatment concentrations of garlic extracts compared, it was found that thesechanges were more related with the application method than the treatmentconcentrations.ANAHTAR SÖZCÜKLER / KEYWORDSSarımsak, Vicia faba L, Hidrojen Peroksit, antimutagenik etki, kromozomalhasarGarlic, Vicia faba L, Hydrogen Peroxide, antimutagenic effect, chromosomalaberration