The prevalence of dyspepsia and affecting factors in patients with chronic renal failure

Gastrointestinal symptoms are common among patients undergoing regular haemodialysis (HD). Gastrointestinal symptoms (GI) may reduced food intake, resulting in malnutrition and impaired well-being in these patients. Malnutrition is associated with increased morbidity and mortality in patients with chronic renal failure (CRF). Very limited data are available on the prevalance of gastrointestinal symptoms in patiens with CRF, although some previous studies have shown a high prevalence of GI symptoms in these patients. The aim of this study was to asses the prevalence of GI symptoms in CRF patients and compare this with healthy population. A total of 640 patients (320 with CRF on hemodialysis, 320 healthy) were invited this study. All of them were given the questionnaire of "Dyspepsia Health Scale" which measures dyspepsia score. The values were compared between CRF and healthy patients. The total dyspepsia score in patients with CRF was significantly higher than healthy populations ( 49.7 % in CRF, 37.5 % in healthy patients) (p<0.002). When comparing CRF patients for dyspepsia there were no relationship in accordance with age, gender, body mass index (BMI), hemodialysis (HD) duration and diabetes mellitus (DM). The dyspepsia score was higher in following situations; smoking, drinking alcohol, history of peptic ulcus , HCV seropositivity and calcium acetate medication for phosphorous binding. The prevalence of dyspepsia is high in patients with CRF than healthy population. The dyspepsia score was higher in following situations; smoking, alcohol, drinking coffe, history of peptic ulcus and H. pylori, HCV seropositivity and calcium acetate medication for phosphorous binding.