Investigation of effect of Malathion on paraoxonase and arylesterase enzyme activities in scaly carp (Cyprinus carpio Linnaeus, 1758)

In this study, it was aimed to reveal the effects on paraoxonase (PON) and arylesterase (ARE) enzyme activities of malathion applied in different concentrations in scaly carp (Cyprinus carpio). For this purpose, 1/2, 1/4 and 1/8 of LC50 concentration value of malathion were exposed to three experimental groups for 21 days. Serum and liver samples on 7, 14 and 21 days collected from fish in the control group and experimental groups which exposed to malathion. Changes in the PON and ARE enzyme activities were determined in the serum and liver samples which collected from fish. The PON and ARE activities in the serum and liver decreased in the groups exposed to malathion compared to that of the control group (p < 0.05). This reduction was statistically different from the control group on 7 and 14 days (p < 0.05). There was no difference in these activities on 21 day (p > 0.05). Key words: Arylesterase, Carp, Cyprinus carpio, Enzyme, Malathion, Pesticide, Paraoxonase.