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Dosimetric comparison of VMAT, IMRT and conformal plans in medulloblastoma radiotherapy: Retrospective study

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2021
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Advisor: Doç. Dr. Candan Demiröz Abakay

Abstract (EN)

DOSIMETRIC COMPARISON OF VMAT, IMRT AND CONFORMAL PLANS IN MEDULLOBLASTOMA RADIOTHERAPY: Retrospective Study In this study, virtual treatment plans were compared for these three techniques using IMRT, VMAT and 3K-BRT treatment planning systems for 8 patients with medulloblastoma who had previously received radiotherapy treatment. Archive materials of 8 patients diagnosed with medulloblastoma who were treated in the Radiation Oncology Department of Bursa Uludağ University Faculty of Medicine were retrospectively obtained and virtual treatment plans were made. In the plans made, a dose of 36 Gy from 1.8 Gy 20 fractions per fraction was determined to be given to the patients. PTV-CTV and critical organs were contoured by doctors for virtual plans. In the plans, attention was paid to the isodose covering 95% of the target volume and protecting critical organs. Dose distributions were obtained with the DVHs in the plans created, and statistical analysis was performed using the Independent-Samples T Test and Mann Whitney U tests in paired comparisons and Anova and Kruskal Wallis tests in triple comparisons with the SPSS program. As a result, no significant difference was found for kidneys, liver and CI values, while the lowest dose of most of them was obtained from the VMAT technique. When the MU value was examined, 3K-BRT superior, the lowest dose value was obtained. In the HI value, although the lowest mean value is 3K-BRT, the minimum and maximum value is VMAT. Keywords: Medulloblastoma, VMAT, Divergence method

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Gözde Parlar

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Gözde Parlar (Master Thesis). Dosimetric comparison of VMAT, IMRT and conformal plans in medulloblastoma radiotherapy: Retrospective study, 2021, Bursa Uludağ Üni̇versi̇ty.

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