The effect of positive psychological intervention on quality of life and well-being in individuals with multiple sclerosis: A randomized controlled trial

This randomized controlled study was conducted to determine the effects of positive psychological intervention on quality of life and well-being in individuals with multiple sclerosis. The study was completed with 21 participants, 11 in the intervention group and 10 in the control group. The intervention group received a four-week positive psychological intervention (writing three good things, writing a gratitude letter, and writing a gratitude journal), while the control group received a daily routine activity (nutrition, hygiene, sleep, and shopping). Data collection tools included an Introductory Information Form, a Feasibility Assessment Form, the Multiple Sclerosis Quality of Life Inventory, the PERMA Scale, and the Positive and Negative Mood Scales. Data were collected from both groups before the intervention, at the 4th week post-intervention, and at the 12th week follow-up. Data were analyzed using the following methods: number, percentage, mean, standard deviation, chi-square test, Mann-Whitney U test, Welch test, Friedman test, and Mixed Design ANOVA. After the positive psychological intervention, the mean positive emotion score in the intervention group (36,10±5,91) differed from the mean positive emotion score in the control group (19,30±10,85) (p<0,001). As a result of the analyses, no significant interaction was found between group, time, and scale for the mean scores of the quality of life and well-being scales (p>0,05). However, the scale and group interaction was found to be significant (p<0,05). The mean composite physical health posttest score in the intervention group decreased but increased at the 12-week follow-up. The mean composite mental health scores increased continuously after the intervention and at the follow-up. In the control group, both the physical and mental health scores increased after the intervention but decreased at the follow-up. The mean well-being score in the intervention group increased after the intervention but decreased at the follow-up. The total mean well-being score of the control group participants decreased over time. In conclusion, it was determined that positive psychological intervention increased positive emotions in individuals with multiple sclerosis and had positive effects on quality of life and well-being. Positive psychological intervention is recommended for individuals with Multiple Sclerosis.