Development and characterization of nanohydroxyapatite doped polymeric nanocomposite membranes

In this study, it is aimed to develop new types of polymeric nanocomposite membranes, which are thought to be used for biomaterial purposes by using membrane technology. For this purpose, firstly, nano hydroxyapatite (nHA) synthesis was carried out. Then, polymethylmethacrylate (PMMA), polysulfone (PS) and polyvinyl alcohol (PVA) polymers were dissolved in the appropriate solvent at a controlled temperature. Polyvinylpyrrolidone (PVP), which is used as a cross linker in the solution, was mixed in dimethylformamide (DMF) at a certain temperature until it became homogeneous and dissolved. Then, both homogeneous solutions were slowly combined and mixed. Certain amounts of prepared nanohydroxyapatite (1%, 3%, 5%, 7%) were added to the solution. It was then spread on a glass plate and left to dry at room temperature. After 12 hours, the layer that dried on the glass plate was left in a bowl filled with distilled water to allow it to solidify and separate from the glass surface. The membranes were stored in distilled water at 4 oC. Characterization processes (FTIR, SEM, SEM-EDS, XRD, AFM) of the prepared polymeric nanocomposite membranes were performed. Due to the similarity of the hydroxyapatite in the content of the prepared membranes to the bone structure, it is thought that the prepared polymeric nanocomposite membrane material can be used in the field of orthopedics after the necessary tests are made.