DSC perfusion MR imaging in non-astrocytic primer central nervous system tumors

PURPOSE: The perfusion MR findings of glial tumors are widely available in the literature. However, there are few studies on DSC perfusion MRI findings of non-astrocytic primer brain tumors such as meningioma, ependymoma, lymphoma, hemangioblastoma, schwannoma, and medulloblastoma. For this reason, our study aimed to reveal perfusion MRI findings of non-astrocytic brain tumors. MATERIALS AND METHODS: 53 patients (15 meningiomas, 13 lymphomas, 13 oligodendrogliomas, 4 ependymomas, 4 schwannomas, 2 medulloblastomas, 2 hemangioblastomas) were included in the study. DSC perfusion MR was applied to all cases on 3T MRI scanner. The maximum rCBV and rCBF values were calculated by ROI technique in all tumors. Comparisons of rCBVmax values with the histological types of the tumors were made with a Oneway ANOVA and Bonferroni Post Hoc tests. P values of less than 0.05 were regarded as statistically significant difference. RESULTS: In our cases, mean rrCBV (mean±S.D.) values were 5.51 ± 2.1 in meningiomas, 3.07 ± 1.63 in lymphomas, 2.49 ± 0.9 in anaplastic oligodendrogliomas, 3.92 ± 2.11 in oligodendrogliomas, 5.77 ± 2.24 in ependymomas, 5.03 ± 1.92 in schwannomas, 1.79 ± 0.97 in medulloblastomas and 7.65 ± 0.91in hemanjioblastomas. There was a statistically significant difference between meningiomas and lymphomas (P<0.033). Although there seemed to be a difference between other tumors acording to rCBV range, p values did not reach statistical significance (P>0.05). CONCLUSION: Perfusion MRI findings may be helpful in distinguishing non-astrocytic brain tumors from other central nervous system tumors. KEY WORDS: meningioma, DSC, perfusion MRI, brain tumor.