Investigation of average values of prolidas, adenozin deaminase, glutathione s-transferase and glutathione reductase enzymes in pancreas cancers

The aim of this thesis study is to provide a general opinion about pancreatic cancer by evaluating the clinical follow-up by evaluating the mean values of prolidase, adenosine deaminase, glutathione reductase and glutathione s-transferase enzymes from blood samples taken from patients diagnosed with pancreatic cancer. The aim of this study was to investigate the mean values of prolidase, adenosine deaminase, glutathione s-transferase and glutathione reductase enzymes in pancreatic cancer; Blood samples were obtained from 20 patients with different age groups ranging from 44 to 75 years, and 20 patients with different complaints from internal medicine, orthopedics and skin clinic. These enzymes were compared with cancer patients and patients with different diseases other than cancer. In this study, mean values of prolidase, adenosine deaminase, glutathione s-transferase and glutathione reductase enzymes were determined from the serum of patients with pancreatic cancer. In literature studies, mean value of GR and GST enzymes decreased in patients with pancreatic cancer (p <0.05), whereas prolidase and adenosine deaminase enzyme activities increased in patients with pancreatic cancer (p <0.05). In conclusion, prolidase, adenosine deaminase, glutathione reductase and glutathione s-transferase enzyme activities may play an important role in the etiopathogenesis of pancreatic cancer.