Anatomic alteration of coronary sinus in left ventrikül diastolic dysfunction and relationshıp with NYHA functionel class

AimsIn our study, we aimed to investigate the relationship beetwen diastolic dysfunction,coronary sinus and NYHA functional capacity.İn our hypothesis,echocardiographic assesment of coronary sinus anatomic alteratin may be part of remodeling process diastolic dysfunctionStudy Design.The study included 121 patients(38 male,83 females) who had LVEF>%50 and diastolic dysfunction by echocardiography .The control grup consisted of 37 patients (22 male,15 females),whose LVEF> %50 and who had normal diastolic function by echocardiography.Plazma NT-proBNP levels were measured.Coronary sinüs size were measured by echocardiography.All patient were evaluated by echocardiyography to examine the relationship between diastolic function,coronary sinüs,NT-proBNP and NYHA functional capacity.ResultsCoronary sinüs size was significantly increased in the diastolic dysfunction grup.( 0.71+0.13 cm ve 0.79+0.17 cm;p=0.006) NT-proBNP levels were significantly increased in the diastolic dysfunction grup. .( 8.99±6.86fmol/ml ve13.74±15.60fmol/ml p=0.010) There was not any relationship between coronary sinüs size and NYHA functional capacity in the diastolic dysfunction grup.(p<0.95) We obtained that patients whose NT-proBNP levels were high have worse functional capacity but it did not reach statistical significance.(p<0.6)Conclusionİn diastolic dysfunction grup,coronary sinüs size was significantly wider than control grup.There is an additional important role of the echocardiographic examination of coronary sinus anatomic alteration in the patients who have diastolic dysfunction.Key Words: ; diastolic dysfunction,coronary sinüs,NYHA functional capacity