Retrospective evaluation of health care associated infection epidemiology in Uludağ University Pediatric Intensive Care and Neonatal Intensive Care Units

Healthcare-associated infections cause increased morbidity, mortality and cost in patients and are a common complication in hospitalized patients. With this study, it was aimed to evaluate the incidence, density, use of invasive vehicles, distribution of factors, risk factors, mortality, costs and their relations with each other of healthcare-associated infections detected between January 2012 and December 2018 in Pediatric and Neonatal Intensive Care Units in our hospital. When the healthcare-associated infections detected in 91 of 2851 patients hospitalized in the Pediatric Intensive Care Unit and in 158 of 2110 patients hospitalized in the Neonatal Intensive Care Unit are analyzed, infection rates were 9.6% and 14.9%, respectively (p<0.001); infection densities, respectively, 9.9 and 7.8/1000 patient days (p= 0.06); catheter-related bloodstream infection rates of 8.2 and 8.6/1000 catheter days (p=0.49); Ventilator-associated pneumonia rates were 5.12 and 5.3/1000 ventilator days (p=0.84). Among all those diagnosed with healthcare-related infections in the Pediatric and Neonatal Intensive Care Units, bloodstream infection was 40.4% and 46.3%, respectively (p=0.144); ventilator-associated pneumonia was found in 27.6% and 26.7% (p=0.792), urinary tract infection in 26.5% and 14.6% (p<0.001). The rate of catheter-related urinary tract infection in the Pediatric Intensive Care Unit was 5.58/1000 urinary catheter days. General mortality rates in Pediatric and Neonatal Intensive Care Units are 9.3% and 20.3%, respectively (p<0.001); 37.4% and 21.5% (p=0.007) of cases with healthcare-associated infections were detected. Use of central catheters, total parenteral nutrition, presence of neutropenia and steroid use in the Pediatric Intensive Care Unit; It was found that the presence of fever and gram-positive growth in the Neonatal Intensive Care Unit increased mortality.