The ri̇sk of mali̇gnancy index (RMI) i̇n adnexial mass comparison to know histopathological
2014
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Advisor: Yrd. Doç. Senem Yaman Tunç
Abstract (EN)
Adnexial masses are commonly seen in gynecologic cases. Malign or benign discrimination should be especially done for those patients suffering from adnexial masses. As prognosis of ovary cancer cases are deteriorite, as it has no previous signals and indications when compared to other disease cases and so establishing final diagnosis lately for the illness, has increased the importance of this disease. In this study we aimed to identify benign-malign adnexial masses in preoperative period better and to foresee malignancy possibility of adnexial masses on higher rate. 212 patients with adnexial masses who had been operated at Dicle University Gynecology Department are added to the study. Malignite Risk Index (RMI) value has been calculated by examining CA-125 level, ultrasonographic indications (bilaterality, solid component, acid presence, metastases presence, multilocularity) and the patient's climacteric status; these rates have been compared to postoperative histopatology diagnosis. By accepting RMI>200 cases as malign, the cases have been examined. When ultrasonographic indications are compared in our own study, it has been seen that bilaterality ve solid area existence have more signifancy to foresee malignity, multilocularity's signifancy the least when compared to the others. It has been seen that there is such a significant difference between RMI rates (p<000.1) in Malign-benign masses. In order to predict malignity it has been seen that RMI CA-125, age and it is more supreme compared to ultrasound score rate. In our study, according to us the most appropriate threshold calculation for RMI and CA-125 has been done. We have noticed that procured thresholds have more sensitivity and specificity as regards rates we were based. It has been seen that there is a great difference between epithelial originated malign ovary tumours and non-epithelial originated malign ovary tumours between RMI rates (p<000.1). As a result RMI is a method with a high sensitivity in preoperative period and specificity, that can applicable easily, not required incremental cost . RMI calculated without the need of any enterprise procedures, and at it will form a foresee at referring malign adnexial masses to tertiary centers and also it will provide adnexial masses to be conducted better. Key words: Ovarian cancer, adnexal masses, risk of malignancy index
Author
Dr. Narin Yar Elmastaş
How to Cite
Narin Yar Elmastaş (Medical Specialty Thesis). The ri̇sk of mali̇gnancy index (RMI) i̇n adnexial mass comparison to know histopathological, 2014, Dicle University.
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