Diagnosis of acute ischemic stroke and transient ischemic attack and severity of illness and the importance of blood cbc parameters

Diagnosis of Acute Ischemic Stroke and Transient Ischemic Attack and Severity of Illness and the Importance of Blood CBC Parameters Several biomarkers researched and are continuing to investigate the diagnosis and assessment of severity of the disease in acute ischemic stroke. There are few studies about the transient ischemic attacks. This study designed for the relationship between blood hemogram parameters and the severity of the disease mortality and imaging findings in patients presenting ischemic stroke and transient ischemic attack clinics to the emergency department In this study, 261 ischemic stroke and 120 transient ischemic attack patients ( total: 381) was included prospectively. Patients with ıschemıc stroke and low scores of Glascow coma score ; RDW (p=0,001) and NLR values were sınıfıcantly higher (p=0,043). The patients with high scores of NIHSS has RDW values were significantly higher (p=0,008). In the first application Modified Rankin Score increament, an increase in the RDW (p <0.0001) was observed. Also one month after; Modified Rankin Score of increases RDW also increased (p <0.0001) was observed. İn the patients with acute ischemic stroke and transient ischemic attack NIHSS score, NLR mean (p = 0.001), RDW mean (p = 0.038) and white blood cell mean (p = 0.006) increament were found. In the first application Modified Rankin Score increament; NLR mean (p< 0,0001), RDW mean increases was observed (p=0,001). Also one month after; Modified Rankin Score increament; NLR mean (p<0,0001), RDW mean (p<0,0001) increament were found. İncreament of the brain infarct in the CT also NLR mean ıncremant accompanied (p= 0,001). Mean of the white blood cells (p=0,050), NLR mean (p= 0,010), MPV mean (p=0,032) increament were also found. The patients who have stenosis over %50 In Carotis doppler USG; NLR values was higher(p=0,020). In patients with serious stenoses NLR mean was found revealed more higher (p = 0.045). Take a look at 30 days mortalıty; who have hıgher levels of RDW mean (p=0,001), NLR mean (p<0,0001), MPV values (p=0,043) have higher mortalıty. Considering the average of the patients who died; hemoglobin levels (p <0.001), hematocrit values (p = 0.003), red blood cell counts (p = 0.023) were lower and white blood cell count (p = 0.018), NLR values (p <0.001), RDW values (p <0.001), troponin values (p <0.001) were higher was observed. MPV, RDW, NLR as easily obtained on the prognosis of patients with stroke and TIA CBC parameters used more in the future as predictive value in emergency practice. Keywords: red blood cell distribution width, mean platelet volume, neutrophil-lymphocyte ratio, ischemic stroke, transient ischemic attack.