Investigation of DNA protective activities effect of Curcuma longa L. and Laurus nobilis L. and against Stenotrophomonas maltophilia

In today's world, rapid development and progress in science and technology have necessitated multipurpose use of natural resources. On the other side, the natural and synthetic antibiotics developed to fight against infectious diseases to date, the resistance of the bottles to build up, the ineffectiveness of the resultant antibiotics and the presence of various side effects have led the experts to search for organic herbal antibiotics. In this study, it was aimed to determine the effects of Extracts of Curcuma longa L.(Zerdeçal) and Laurus nobilis L.(Defne) Plants on the DNA protective activity and Stenotrophomonas maltophilia strains which are influencing the hospital infection. Water, Methanol, Hexane, Dichloromethane extracts were prepared and exposed to H2O2 and UV light with pBR322, the results were displayed on gel. The results showed that Curcuma longa (Zerdeçal) water and methanol, Laurus nobilis (Defne) water extracts are the DNA protecting properties from oxidative damage. As a result of disc diffusion test studies on S. maltophilia strains, it was determined that the extracts did not show antibacterial activity on the bacteria. The results obtained can be evaluated in the future in the construction of sun creams and sun lotions in the cosmetic industry.