Determination of Beta-Lactam antibiotics in unpacked cheeses

For all individuals around the world, milk is a key component of a balanced diet. In addition to milk, many dairy products have been produced and eaten worldwide, such as cream, yogurt, butter, cheese, and kefir. There are several research and studies about the effect of milk and dairy products on people health for this cause. Antimicrobial medications are used for both prophylactic and medicinal uses in industrial milk farming systems. In lactating animals, penicillins, aminoglycosides, tetracyclines, and sulphonamides were commonly used, resulting in the pre,sence of their res.idues in milk. Dr.ugs are commonly used to promote the health of cattle, to cure diseases and to increase production. One of the big concerns related to the use of anti.biotics in an.imals is mastitis. Milk containing antibiotics triggers resistance to pathogenic microorganisms. In certain individuals, they cause allergic reactions and therefore cause harmful effects. In this research, 100 cheese samples were analyzed. These samples were analyzed by MiRA as a qualitative analysis; the Beta lactam ELISA test also conducted quantitative checks for antibiotic residue. Finally, positive results was observed by both methods in 6 (6%) of 100 samples. According to these results, the antibiotic residue issue in milk and milk products still persists. On the other hand, the beta lactam levels in the lower limits of the samples have been evaluated as promising when all the studies are reviewed. However, with further examples, these experiments should be improved and milk and dairy products should be systematically evaluated in terms of hygiene requirements. Since it is important to analyze food compounds not just for antibiotic residues, but also contaminants such as mycotoxins, hormones and heavy metals. Keywords: Cheese, Antibiotic, Beta-Lactam, Elisa, Mira Test