Evaluation of apelin and some biochemical parameters in coronary artery patients in mosul city

The present case control study was performed from September 2022until April 2023 at Çankırı Karatekin Üniversitesi/ Department of Biochemistry on 78 patients of different ages with heart disease (such as coronary artery disease also called coronary heart disease or heart disease or myocardial ischemia) who were diagnosed in Mosul hospitals and were compared with the control group, which included 67 samples of healthy people, when measuring the concentration of Apelin, it was found that there was a significant decrease in the concentration of Apelin in people suffering from heart disease compared with the control group in which the concentration of Apelin was within normal rates, as it acts as a protective system of the body. A group of biochemical variables were measured and the correlation relationship was statistically found between their concentrations and the concentration of Apelin and the results of the study were as follows A significant increase in the concentration of urea, creatinine and uric acid in the blood of people suffering from heart disease was found compared with the control group, which was within the normal concentrations of biochemical variables, where the correlation with the concentration of Apelin was inversely related, as the higher the concentration of these variables, in turn, the lower the concentration of Apelin and the greater its effect on heart disease, while the higher the concentration of Aeplin reduces the effects on the heart .It was also noted that there is a significant increase in both cholesterol and triglycerides compared to the concentration of Apelin in patients, and it was also found that there is a significant decrease in the concentration of high-density lipids, as well as there is a significant decrease in enzymatic antioxidants, such as catalase enzyme, compared with the concentration of Apelin in patients. While we found no significant differences in the concentration of albumin, the concentration of sodium and calcium salts and the enzyme ALT compared with the concentration of Apelin in the blood.