Evaluati̇on of morbi̇di̇ty and mortali̇ty of pati̇ents wi̇th lung cancer operated i̇n our cli̇ni̇c

ABSTRACT Introduction Lung cancer accounts 12.8% of all cancer types and causes 17.8% of cancer related deaths. The surgically resected group has the best survival period especially in early stage lung cancer among all lung cancer population. The most important prognostic factor is being of nodal metastasis in non small cell lung cancer patients. The aim of this study is to compare the results of the 6 th and 7 th staging system , histopathologic subtypes and resection types of non small cell lung cancer in prognosis and survival period. Material and Methods We retrospectively evaluated 120 lung resection patients with nonsmall cell lung cancer in thoracic surgery department of Medical School, Dicle University between January 2000 and January 2013. Radiological findings, histopathological results, 6th and 7th staging system determined results were noted for every patients. Patients were evaluated for gender, age, diagnostic methods, type of surgical resection, postoperative complications, cancer staging. Survival periods for one and five years of patients were determined and factors affecting survival were noted. The 6th and 7th lung cancer staging systems were compared for survival periods. Results Of the patients, 90% (n:108) were male and 10% (n:12) were woman. The first year survival was 81.6% and the fifth year suvival was 45.5%. At the admission, the most common symptom was chest pain (53.7%). The rate of smoker patients were 91.6% . Preoperative diagnosis was established for 62.5% (n:75) gf the cases. Methods for preoperative diagnosis were bronchoscopy in 45, transthoracic needle aspiration byopsy in 30 patients. Frozen section diagnosis were used for 45 patients during explorative thoracotomy. The most common lung resection types were lobectomy in 55% and pneumonectomy in 27%. The most common histopathologic diagnosis was epidermoid lung carcinoma in 55 patients (45.8%). Complete anatomic resections were done in 89% (n:107), incomplete non anatomic resections were done in 5.8% (n:7) and 5% (n:6) of the cases were intraoperatively decided unresectable. The most common postoperative complication was prolonged air leakage in 10.8% (n:13). In spite of Stage 1B was the most common stage according to the 6th staging system, stage 1A was most common stage in 7th staging system. Stage of 1A has the best survival ratio for 5 years for both staging systems. Survival rates of 5 years were 88% for stage 1A, 53.8% for stage 1B for 6th staging system and 85.7% for stage 1A, 53.8% for stage 1B and 50% for stage 2A for 7th staging system. Conclusion The 7th staging system has superior value than 6th system for measure of the extent of disease, which is used to guide management and determine prognosis.