Lumbar disc surgery, postoperative for analgesia I.V. relief trometamol and placebo comparison

In this study we aimed at researching the effect of 50 mg deksketoprofen trometamol, which was administered to the patients who had microchirurgyc lumbar discectomy preoperative and postoperative in 3 doses I.V. with 8-hour intervals, on postoperative VAS scores and 24-hour total tramadol consumption and patient satisfaction.Our study was carried out double blind, prospective and randomized on 50 patients at the age range of 18-65, weight range of 50-120 kgs, in risk group of ASA I ? II and planned to be administered microchirurgyc lumbar discectomy at neurosurgery clinic. The Group I was administered I.V. 50 mg of deksketoprofen trometamol just before induction and one dose of deksketoprofen trometamol was administered at the 8. and 16. hours after the first dose was administered. The Group II (control group) was administered placebo at the 8. and 16. hours pre and postoperative. Both groups were administered tramadol 24 hours via HKA device I.V. postoperative. Level of analgesia in patients was evaluated through visual analogue scale (VAS) at the 0.,15., 30., 45., 60. minutes and 2., 3., 4., 5., 6., 8., 12., 24. hours. Consumption of tramadol was recorded. Analgesic efficiency of deksketoprofen trometamol and its effect on consumption of tramadol were compared.VAS scores of Grup I were found significantly lower compared to those of Grup II (P< 0,001). Comparing all-time consumption of tramadol of Group I with Group II, consumption of tramadol was found lower in Group I at 30. and 60. minutes (P < 0,05)while no difference was observed at the 15. and 45. minutes between the groups(P > 0,05). Tramadol consumption of Group I in other time periods was found significantly lower compared to Group II (P < 0,001). As for the total tramadol consumption, it was found significantly lower in Group I compared to Group II(P< 0,001). When comparing the first analgesic demand time of Group I and Group II, it was in Group I that was found significantly long(P<0,05). Comparing overall patient satisfaction in Group I and Group II, it was established better in Group I(P<0,05).Consequently; we came to the conclusion that 50 mg deksketoprofen trometamol that we used I.V. preoperative and postoperative after herniated disc surgery is reliable and active in the treatment of postoperative pain, it decreases opioid use, and it is more advantageous than the use of opioid alone.