The new melatonin dervative, its some biological activities and HPLC application
2019
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Advisor: Prof. Dr. Mustafa Karatepe
Abstract (EN)
In this study, it is aimed to synthesize a new derivative of melatonin and evaluate the biological properties of this new derivative as well as to develop a new method for analyzing HPLC. In the first step, the new derivative of this compound was prepared with benzyl chloride. The purity control of the obtained derivative was made by means of melting point and the chemical structure was confirmed by IR, 1H NMR and 13C-NMR spectral analyses and results with elemental analysis were supported. In the second step, antimicrobial and antioxidant properties of synthesized melatonin derivative were investigated using different microorganism and antioxidant methods. In the last step, the method for the analysis of the new derivative in biological sample by HPLC-UV was developed.
Author
Dr. Srwa Hashım Mohammed Al-nabawı
Institution
How to Cite
Srwa Hashım Mohammed Al-nabawı (Master Thesis). The new melatonin dervative, its some biological activities and HPLC application, 2019, Fırat University.
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