The relationship between insulin resistance and obstructive sleep apnea syndrome independent of obesity

8.İntroduction: The relationship between insulin rezistance and AHİ that indicates OSAS seriousness and also the relationship betweeb insülin resistance and low O2 saturation are showed. The meaningful corelation between the hipoksemi severity related with sleep and the insulin resistance, supports that there is relationship between the metabolic effects of sleeping apne and O2 dasaturation because of apne or hipoapne. İn this study, we search the relationship between obstructive sleeping apne sendrom (OSAS) and the insulin resistance independent from obesity.Material-method: 40 Pations who apply chest policlinics between the dates july 2007-may 2008 are tied to polysomnografi 13 patients of 40 get diagnosis as OSAS and they form the first group. The rest who dont get diagnosis as OSAS form the second group and all of them are searched for insülin resistance.Findings: All of the frist group,involver 13 patients who have OSAS, have insulin resistance but insulin resistance are found out at only 11 patients of the second group, involve who dont have OSAS. These results are not meaningful for the two groups. But, although all the members of two groups are obes, the first group have more high insulin resistance than the second.Results: At this study, we cant indicate the direct relationship between OSAS and insülin resistance but according to the other studies we can say that insülin resistance progress is multifactorial and obesity is the major sign Aspecially after the decrease of insülin resistance at the third day of CPAP cure, we think that the obesity is nat sole factor. We need comparative, prospective studies which have big groups of patients who are known for a long time.