The relation between serum glucose and insulin with hypothyroidism in middle aged women

The most common endocrine disorders in the general population are diabetes and thyroid disorders. In hypothyroidism, glucose metabolism is affected by a variety of mechanisms, including impaired genetic expression of genes, overproduction of hepatic glucose output, and increased absorption of splanchnic glucose, with physiological abnormalities leading to impaired glucose utilization and excretion in muscles. Hypothyroidism is at least twice as common in women as in men. Although hypothyroidism is most common in middle-aged or older women, the disease can occur at any age. In this study, middle-aged women (aged 45-65 years) were selected, who were previously diagnosed with hypothyroidism and did not have other chronic diseases. This study investigated the incidence of T1DM and T2DM in patients with pre-existing hypothyroidism and determined the incidence of hypothyroidism with pre-existing T1DM and T2DM. It has been observed that female patients between the ages of 45 and 65 who were diagnosed with hypothyroidism have a risk of developing diabetes. The risk of developing hypothyroidism in female patients aged 45–65 years diagnosed with diabetes was evaluated as positive based on the results of two of the three markers.